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It was discovered that naltrexone and bupropion combined, which may be marketed later on as Contrave, have better weight loss results than eating and working out alone.

Using two separate drugs to shed pounds can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you ought to err assisting caution and permit the FDA do its job and demand some investigation be done so your public recognizes the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to generate money and that they would say almost anything to keep people on the medications.

Researchers discovered that participants taking this drug for any year, lost weight within one month and have kept the body weight off throughout the 56 weeks from the study. Contrave is a combination with the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which are made up of more than one active ingredient, which can make them far better and safer.

Combo-pilling could be the newest fad or even better the newest ahead under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular is the fact that since right now there aren't any long term prescription diet pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug may also raise blood pressure level and heartbeat, and shouldn't be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high hypertension, in addition to by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.


Other people who should not use Contrave are patients being affected by bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave really should not be prescribed for women who are pregnant or looking to become pregnant.

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